Diabetapedia definition: A hormone produced by pancreatic beta cells that is co‐created with insulin and works synergistically with insulin to lower blood sugar level. Amylin plays a role in glycemic regulation by slowing gastric emptying and promoting satiety, thereby preventing post‐prandial spikes in blood glucose level.

Amylin functions as part of the endocrine pancreas and contributes to glycemic control. The peptide is secreted from the pancreatic islets into the blood circulation and is cleared by peptidases in the kidney.

It is not found in the urine.

Reference: National Diabetes Information Clearinghouse

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